Texas A&M researchers report nasal spray therapy reversed signs of brain aging and improved memory in preclinical study

Texas A&M scientists developed a nasal spray that reduced brain inflammation, restored cellular energy function, and improved memory after just two doses. The effects appeared within weeks and lasted for months, suggesting a potential new path for treating neuroinflammaging and age-related cognitive decline.

If the results translate beyond preclinical models, noninvasive delivery could become a major advantage for future brain-aging and Alzheimer’s-related therapies. The work reflects a broader trend toward targeting inflammation and cellular repair mechanisms rather than only treating symptoms of neurodegeneration.